WB (1:5000). Other applications have not been tested. The optimal dilutions should be determined by end user.
限制
仅限研究用
状态
Liquid
缓冲液
TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
储存液
Sodium azide, Thimerosal (Merthiolate)
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
有效期
12 months
抗原
TTR
(Transthyretin (TTR))
别名
Prealbumin, PA
背景
Prealbumin (PA), as known as Transthyretin (TTR), is an evolutionarily conserved serum and cerebrospinal fluid (CSF) protein that transports holo-retinol-binding protein (RBP) and thyroxine (T4). It is a 62-kDa homotetramer with a dimer of dimers quaternary structure that is synthesized mainly in liver, choroid plexus, retinal pigment epithelium for secretion into the bloodstream, cerebrospinal fluid and the eye, respectively. It maintains normal levels of retinol, retinol-binding protein, and thyroid hormone in the circulating plasma. TTR misfolding and aggregation is known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC).